Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704203 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HPGDRAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL6907425 | 0.67 | DYRK1A (0.54) | ALDH1A1HPGDRAB9ASMN1; SMN2DYRK1A | |
| Hypoxanthine SCHEMBL25381 | 0.62 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 | |
| Hypoxanthine SCHEMBL30096461 | 0.62 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 | |
| Hypoxanthine SCHEMBL7037918 | 0.62 | ALDH1A1 (1.00) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 | |
| SCHEMBL21895454 | 0.62 | ALDH1A1 (0.41) | ALDH1A1HPGDRAB9ASMN1; SMN2DYRK1A | |
| SCHEMBL21273002 | 0.61 | PIM1 (0.43) | ALDH1A1HPGDRAB9ASMN1; SMN2DYRK1A | |
| Hypoxanthine SCHEMBL7168422 | 0.61 | ALDH1A1 (0.95) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 | |
| Hypoxanthine SCHEMBL2639254 | 0.61 | ALDH1A1 (0.95) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 | |
| Hypoxanthine SCHEMBL122843 | 0.61 | ALDH1A1 (0.95) | ALDH1A1RAB9ASMN1; SMN2TP53HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0961775-A2 | PURINE L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN Pharmaceuticals, Inc. (US) | 1999-12-08 | — | — | EP | disclosed |
| WO-1998016184-A2 | PURINE L-NUCLEOSIDES, ANALOGS AND USES THEREOF | ICN PHARMACEUTICALS, INC. (US) | 1998-04-23 | — | — | WO | disclosed |