Styrene

Styrene

SCHEMBL8466012

C=Cc1ccccc1.O=C1C=C(C2CCCCC2)C(=O)N1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.39
PTPRC P08575 1/20 0.39
PTPRF P10586 1/20 0.39
CDC25B P30305 1/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 1/20 0.39
METAP1 P53582 2/20 0.33
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
MAPT P10636 2/20 0.32
MAPK1 P28482 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 1/20 0.32
RAB9A P51151 1/20 0.32
HPGD P15428 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27578984 0.93 PTPN1 (0.35) PTPN1PTPRCPTPRFCDC25BALDH1A1
Styrene SCHEMBL531439 0.82 HPGD (0.30) HPGD
Vinyl Chloride SCHEMBL379531 0.82 MAOA (0.37) PTPN1PTPRCPTPRFCDC25BMAOA
SCHEMBL28123322 0.82 MAOA (0.44) PTPN1PTPRCPTPRFCDC25BMAPT
SCHEMBL9250741 0.82 MAOA (0.44) PTPN1PTPRCPTPRFCDC25BMAPT
SCHEMBL28720 0.82 MAOA (0.44) PTPN1PTPRCPTPRFCDC25BMAPT
SCHEMBL8885354 0.82 MAOA (0.44) PTPN1PTPRCPTPRFCDC25BMAPT
Ammonia Solution, Strong SCHEMBL27877904 0.80 MAOA (0.42) PTPN1PTPRCPTPRFCDC25BMAPT
SCHEMBL27630042 0.80 MAOA (0.45) PTPN1PTPRCPTPRFCDC25BMAOA
SCHEMBL9490474 0.79 PTPN1 (0.40) PTPN1PTPRCPTPRFCDC25BTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4161449-A None JP disclosed
EP-0634445-B1 Light diffuser composition DOW CHEMICAL CO (US) 1999-08-11 EP disclosed
EP-0634445-A1 Light diffuser composition THE DOW CHEMICAL COMPANY (US) 1995-01-18 EP disclosed
JP-H04161449-A LIGHT DIFFUSING RESIN COMPOSITION MITSUBISHI GAS CHEM CO INC 1992-06-04 JP disclosed