SCHEMBL8466360

SCHEMBL8466360

[c]1cc[c]c(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.55
BCL2 P10415 1/20 0.39
BCL2L1 Q07817 1/20 0.39
LTA4H P09960 1/20 0.38
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.38
IDO1 P14902 1/20 0.38
TP53 P04637 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
TRPA1 O75762 1/20 0.38
KDM4E B2RXH2 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
IDH1 O75874 1/20 0.37
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
HTR2A P28223 1/20 0.37
MAOB P27338 1/20 0.36
HPGD P15428 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721135 0.80 CALM1 (0.44) CALM1BCL2BCL2L1CYP3A4HTR2A
SCHEMBL7465411 0.80 CALM1 (0.44) CALM1BCL2BCL2L1ALDH1A1TSHR
SCHEMBL7459473 0.78 CALM1 (0.42) CALM1BCL2BCL2L1LTA4HALDH1A1
SCHEMBL7453243 0.78 CALM1 (0.42) CALM1BCL2BCL2L1LTA4HALDH1A1
SCHEMBL28815316 0.78 CALM1 (0.42) CALM1ALDH1A1LOXL2CYP3A4HTR2A
SCHEMBL1551925 0.78 BCL2 (0.45) CALM1BCL2BCL2L1CYP3A4IDH1
SCHEMBL10384790 0.78 CALM1 (0.61) CALM1BCL2BCL2L1LTA4HALDH1A1
SCHEMBL8939781 0.77 CALM1 (0.41) CALM1BCL2BCL2L1LTA4HALDH1A1
SCHEMBL1395580 0.77 CALM1 (0.41) CALM1ALDH1A1TSHRKDM4EMAPT
SCHEMBL8802600 0.77 BCL2 (0.44) CALM1BCL2BCL2L1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942947-A1 FLAME-RESISTANT THERMOPLASTIC MOULDING COMPOUNDS BASED ON POLYARYLENE ETHERS BASF AKTIENGESELLSCHAFT (DE) 1999-09-22 EP disclosed
WO-1998024838-A1 FLAME-RESISTANT THERMOPLASTIC MOULDING COMPOUNDS BASED ON POLYARYLENE ETHERS BASF AKTIENGESELLSCHAFT (DE) 1998-06-11 WO disclosed