Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | LDHB | P07195 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8160322 | 0.92 | PTPN1 (0.43) | PTPN1PTPN11COMTMAPTPTPN2 | |
| SCHEMBL8466539 | 0.82 | PTPN1 (0.38) | PTPN1PTPN11CDK2COMTLMNA | |
| SCHEMBL8154162 | 0.81 | PTPN1 (0.49) | PTPN1PTPN11LMNAMAPTXBP1 | |
| SCHEMBL5587114 | 0.76 | PTPN1 (0.49) | PTPN1PTPN11COMTPTPN2MCL1 | |
| SCHEMBL8161795 | 0.71 | GPR35 (0.47) | PTPN1CDK2LMNAMAPTHIF1A | |
| SCHEMBL27884911 | 0.70 | HTT (0.41) | PTPN1PTPN11COMTGPR35 | |
| Hydrochloric Acid SCHEMBL8154209 | 0.69 | PTPN1 (0.46) | PTPN1PTPN11LMNAMAPTXBP1 | |
| SCHEMBL5587190 | 0.69 | BID (0.43) | PTPN1PTPN11COMTMAPTMCL1 | |
| SCHEMBL5590085 | 0.69 | CA1 (0.41) | PTPN1PTPN11CDK2COMTMAPT | |
| SCHEMBL8374510 | 0.68 | PPARA (0.41) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883129-A | Hydroxylated anthranilic acid derivatives | ASTRA AKTIEBOLAG (SE) | 1999-03-16 | — | — | US | disclosed |