Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 3/20 | 0.35 |
| ▸ | HMGCR | P04035 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466537 | 0.82 | PTPN1 (0.40) | PTPN1PTPN11PTPN2COMTMAPT | |
| SCHEMBL8160322 | 0.78 | PTPN1 (0.43) | PTPN1PTPN11PTPN2COMTMAPT | |
| SCHEMBL8154162 | 0.72 | PTPN1 (0.49) | PTPN1PTPN11PTPN2HMGCRMAPT | |
| SCHEMBL5587114 | 0.70 | PTPN1 (0.49) | PTPN1PTPN11PTPN2COMT | |
| SCHEMBL5587190 | 0.63 | BID (0.43) | PTPN1PTPN11COMTMAPTPTGES | |
| SCHEMBL5590085 | 0.63 | CA1 (0.41) | PTPN1PTPN11COMTMAPTHIF1A | |
| SCHEMBL5590143 | 0.62 | BID (0.48) | PTPN1MAPTPTGESTOP2AKDM4E | |
| SCHEMBL5587709 | 0.62 | PTPN1 (0.51) | PTPN1PTPN11PTPN2HMGCRPTGES | |
| SCHEMBL4674060 | 0.62 | CA1 (0.44) | MAPTLMNAPKMCDK2KDM4E | |
| SCHEMBL5587237 | 0.61 | BID (0.50) | PTPN1MAPTPTGESTOP2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883129-A | Hydroxylated anthranilic acid derivatives | ASTRA AKTIEBOLAG (SE) | 1999-03-16 | — | — | US | disclosed |