Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18742136 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL18742133 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL17010250 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL3271592 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL3271401 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL7154001 | 0.85 | FAAH (0.62) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL16474 | 0.83 | FAAH (0.59) | KMT2AFAAHMEN1MAPK1POLB | |
| SCHEMBL8478492 | 0.82 | KMT2A (0.46) | KMT2AFAAHMEN1MAPK1ALDH1A1 | |
| SCHEMBL8478495 | 0.82 | KMT2A (0.46) | KMT2AFAAHMEN1MAPK1ALDH1A1 | |
| SCHEMBL8467106 | 0.82 | FAAH (0.56) | KMT2AFAAHMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981580-A | IN WHICH THE CARBOXY-TERMINUS HAS BEEN MODIFIED TO FORM VARIOUS AMIDES, ESTERS, KETONES, ALCOHOLS, ALCOHOL ESTERS AND NITRITES THEREOF, AND ARE USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME | G. D. SEARLE & CO. (US) | 1999-11-09 | — | — | US | disclosed |
| WO-1999050229-A1 | FATTY ACID ANALOGS AND PRODRUGS | G.D. SEARLE & CO. (US) | 1999-10-07 | — | — | WO | disclosed |