Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478492 | 1.00 | KMT2A (0.46) | KMT2AMEN1FAAHMAPK1POLB | |
| SCHEMBL8467034 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL8467037 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL8468115 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL8468116 | 0.86 | ALDH1A1 (0.47) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL8466609 | 0.82 | KMT2A (0.50) | KMT2AMEN1FAAHMAPK1POLB | |
| SCHEMBL12350038 | 0.80 | FAAH (0.57) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL18796566 | 0.80 | FAAH (0.57) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL13295483 | 0.80 | FAAH (0.57) | KMT2AMEN1FAAHMAPK1ALDH1A1 | |
| SCHEMBL13425382 | 0.80 | FAAH (0.57) | KMT2AMEN1FAAHMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952377-A | SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME, AS ANTI-VIRAL AND ANTI-FUNGAL AGENTS OR PRO-DRUGS; TREATING AIDS, LENTIVIRUSES SUCH AS THE HUMAN IMMUNODEFICIENCY VIRUS | G. D. SEARLE & CO. (US) | 1999-09-14 | — | — | US | disclosed |