Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16047247 | 0.81 | KMT2A (0.52) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL1765880 | 0.81 | KMT2A (0.45) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL8468500 | 0.80 | LMNA (0.42) | KMT2AMAPTTDP1MAPK1CYP3A4 | |
| SCHEMBL31315054 | 0.79 | KMT2A (0.50) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL1520392 | 0.77 | KMT2A (0.58) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL4201591 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL7909243 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL1641518 | 0.77 | HDAC3 (0.55) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL11421328 | 0.77 | ALDH1A1 (0.52) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL31131464 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |