Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22616327 | 0.83 | KMT2A (0.46) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL16047247 | 0.81 | KMT2A (0.52) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL31131465 | 0.80 | KMT2A (0.47) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL31315054 | 0.79 | KMT2A (0.50) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL8466797 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL1520392 | 0.77 | KMT2A (0.58) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL1641518 | 0.77 | HDAC3 (0.55) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL11421328 | 0.77 | ALDH1A1 (0.52) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL7909243 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 | |
| SCHEMBL31131464 | 0.77 | KMT2A (0.49) | KMT2AGSK3BPTPN1GPR139CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11597926-B2 | Thiophosphoramidites | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-03-07 | — | — | US | claimed |
| US-20210115438-A1 | NOVEL THIOPHOSPHORAMIDITES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-04-22 | — | — | US | claimed |
| EP-3728590-A1 | NOVEL THIOPHOSPHORAMIDITES | Roche Innovation Center Copenhagen A/S (DK) | 2020-10-28 | — | — | EP | claimed |
| CN-111448316-A | Novel thiophosphorous acid amides | 罗氏创新中心哥本哈根有限公司 | 2020-07-24 | — | — | CN | claimed |
| US-11597926-B2 | Thiophosphoramidites | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-03-07 | — | — | US | disclosed |
| US-20230002762-A1 | OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2023-01-05 | — | — | US | disclosed |
| EP-4092117-A1 | GAPMER OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | Roche Innovation Center Copenhagen A/S (DK) | 2022-11-23 | — | — | EP | disclosed |
| US-20220204540-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2022-06-30 | — | — | US | disclosed |
| US-11365175-B2 | Aromatic amides having a fungicidal activity, their agronomic compositions and relative preparation method | ISAGRO S.P.A. (IT) | 2022-06-21 | — | — | US | disclosed |
| EP-3962900-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ISAGRO S.p.A. (IT) | 2022-03-09 | — | — | EP | disclosed |
| US-20210115438-A1 | NOVEL THIOPHOSPHORAMIDITES | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2021-04-22 | — | — | US | disclosed |
| US-20200354314-A1 | AROMATIC AMIDES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE PREPARATION METHOD | BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT | 2020-11-12 | — | — | US | disclosed |
| US-6987112-B2 | Organic compound having cyano group and insecticides/miticides | NIPPON SODA CO., LTD. (US) | 2006-01-17 | — | — | US | disclosed |
| US-20050233995-A1 | Immunostimulatory nucleic acid molecules | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-10-20 | — | — | US | disclosed |
| US-20040235761-A1 | Novel virus proliferaton inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-11-25 | — | — | US | disclosed |
| EP-1417967-A1 | NOVEL VIRUS PROLIFERATION INHIBITION/VIRUCIDAL METHOD AND NOVEL PYRADINE NUCLEOTIDE/PYRADINE NUCLEOSIDE ANALOGUE | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-05-12 | — | — | EP | disclosed |
| US-20040072826-A1 | Organic compound having cyano group and insecticides/miticides | NIPPON SODA CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1338589-A1 | ORGANIC COMPOUND HAVING CYANO GROUP AND INSECTICIDES/MITICIDES | NIPPON SODA CO., LTD. (JP) | 2003-08-27 | — | — | EP | disclosed |
| EP-0903346-A1 | SYDNONE IMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-4340728-A | ANTITUMOR AGENT OF 5-FLUORO URIDINE OR URACIL DERIVATIVE | FUJI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1982-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002762-A1 | OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEOSIDE LINKAGE | DUT, TYMP, TYMS | KMT2A 2877/4885GSK3B 3837/4885PTPN1 2570/4885 |
| US-20220204540-A1 | ESTERS OF NON- AROMATIC HETEROCYCLIC COMPOUNDS HAVING A NEMATOCIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND USE THEREOF | ACHE, CYP51A1, DNPH1 | KMT2A 1357/4885GSK3B 4501/4885PTPN1 678/4885 |
| US-20200354314-A1 | AROMATIC AMIDES HAVING A FUNGICIDAL ACTIVITY, THEIR AGRONOMIC COMPOSITIONS AND RELATIVE PREPARATION METHOD | CYP51A1, NAT1, AADAC | KMT2A 394/4885GSK3B 3139/4885PTPN1 2103/4885 |
| US-11365175-B2 | Aromatic amides having a fungicidal activity, their agronomic compositions and relative preparation method | CYP51A1, NAT1, AADAC | KMT2A 394/4885GSK3B 3139/4885PTPN1 2103/4885 |
| US-20210115438-A1 | NOVEL THIOPHOSPHORAMIDITES | TYMP, RRM2B, RNGTT | KMT2A 1212/4885GSK3B 2710/4885PTPN1 514/4885 |
| US-20040072826-A1 | Organic compound having cyano group and insecticides/miticides | ACHE, OTC, MT-CO1 | KMT2A 1239/4885GSK3B 1690/4885PTPN1 816/4885 |
| US-11597926-B2 | Thiophosphoramidites | TYMP, RRM2B, RRM2 | KMT2A 1594/4885GSK3B 2117/4885PTPN1 454/4885 |
| US-20040235761-A1 | Novel virus proliferaton inhibition/virucidal method and novel pyradine nucleotide/pyradine nucleoside analogue | CDK5, NT5C3B, CDK15 | KMT2A 1499/4885GSK3B 3415/4885PTPN1 1579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.