SCHEMBL8466923

SCHEMBL8466923

CCc1[c]c(CS)ccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL177278 0.87 GABRA1 (0.38) GABRA1GABRB2
SCHEMBL8465952 0.82
SCHEMBL28322651 0.78 GABRA1 (0.37) GABRA1GABRB2
SCHEMBL8465606 0.76
SCHEMBL820116 0.76 GABRA1 (0.31) GABRA1GABRB2
SCHEMBL27314062 0.76 LOXL2 (0.35) GABRA1GABRB2
SCHEMBL177368 0.73
SCHEMBL819446 0.73 KCNH2 (0.36)
SCHEMBL1777119 0.73 GABRA1 (0.39) GABRA1GABRB2
Lithium Ion SCHEMBL753322 0.73 GABRA1 (0.38) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883044-A Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners ROHM AND HAAS COMPANY (US) 1999-03-16 US claimed
US-5883044-A Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners ROHM AND HAAS COMPANY (US) 1999-03-16 US disclosed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
US-5693590-A PLANT GROWTH REGULATOR ROHM AND HAAS COMPANY (US) 1997-12-02 US disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed