Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8463421 | 0.91 | RAB9A (0.33) | RAB9AALDH1A1NPC1TP53SMN1; SMN2 | |
| SCHEMBL8677279 | 0.91 | RAB9A (0.33) | RAB9AALDH1A1NPC1TP53SMN1; SMN2 | |
| Butadiene SCHEMBL8465296 | 0.89 | RAB9A (0.33) | RAB9AALDH1A1NPC1TP53SMN1; SMN2 | |
| SCHEMBL8677042 | 0.81 | HSD11B1 (0.31) | — | |
| SCHEMBL8678494 | 0.80 | ALDH1A1 (0.37) | RAB9AALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL8581525 | 0.79 | ALDH1A1 (0.33) | ADCY1RAB9AALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8465566 | 0.77 | — | — | |
| SCHEMBL8678366 | 0.77 | — | — | |
| SCHEMBL8523353 | 0.76 | — | — | |
| SCHEMBL8463610 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767795-B1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | DOW CHEMICAL CO (US) | 1999-12-22 | — | — | EP | disclosed |
| US-5770538-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1998-06-23 | — | — | US | disclosed |
| EP-0767795-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1997-04-16 | — | — | EP | disclosed |
| US-5486632-A | Group 4 metal diene complexes and addition polymerization catalysts therefrom | THE DOW CHEMICAL COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1996000734-A1 | GROUP 4 METAL DIENE COMPLEXES AND ADDITION POLYMERIZATION CATALYSTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |