Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468011 | 0.89 | SIGMAR1 (0.37) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL104783 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL20870720 | 0.80 | TYR (0.46) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL6284683 | 0.78 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL2443506 | 0.77 | FDPS (0.40) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL6284703 | 0.76 | SIGMAR1 (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL6203856 | 0.76 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL23280361 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL1450096 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3SIGMAR1CYP3A4 | |
| SCHEMBL234864 | 0.75 | CYP3A4 (0.53) | SIGMAR1CYP3A4ALOX15CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |