Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2443506 | 0.85 | FDPS (0.40) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| SCHEMBL104783 | 0.83 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| SCHEMBL11202361 | 0.82 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| SCHEMBL28133134 | 0.80 | SLC6A2 (0.38) | TYRSLC6A2SLC6A4SLC6A3FDPS | |
| SCHEMBL8467467 | 0.80 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| SCHEMBL16197829 | 0.79 | FDPS (0.39) | SLC6A2SLC6A4SLC6A3FDPSALOX15 | |
| SCHEMBL4931748 | 0.79 | FDPS (0.39) | SLC6A2SLC6A4SLC6A3FDPSALOX15 | |
| SCHEMBL28107515 | 0.78 | FDPS (0.36) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| SCHEMBL6284683 | 0.78 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 | |
| Formic Acid SCHEMBL28259321 | 0.78 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3FDPSSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239454-A1 | SULFONYL SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-07-30 | — | — | US | disclosed |
| WO-2019063015-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS RORγ INHIBITOR | 正大天晴药业集团股份有限公司 | 2019-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239454-A1 | SULFONYL SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR | RORC, RORA, RORB | TYR 2756/4885SLC6A2 4668/4885SLC6A4 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.