Acrylic Acid

Acrylic Acid

SCHEMBL8467600

C=CC(=O)O.CC(O)CC=C(CC(C)O)C(=O)O

nearest known ligand 0.45

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 7/20 0.45
GRIK2 Q13002 4/20 0.40
LMNA P02545 1/20 0.36
ALOX15 P16050 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRIA2 P42262 2/20 0.33
GRIA4 P48058 2/20 0.33
GRIK3 Q13003 2/20 0.33
GRIK5 Q16478 2/20 0.33
GRIA1 P42261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10942638 0.91 GRIK1 (0.52) GRIK1GRIK2GRIA2GRIA4GRIK3
Acrylic Acid SCHEMBL29845216 0.78 LMNA (0.39) LMNAALOX15HSD17B10
SCHEMBL9073285 0.75 GRIK1 (0.43) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL9410934 0.73 TSHR (0.45) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL6130626 0.73 GRIK1 (0.38) GRIK1
Acrylic Acid SCHEMBL28013920 0.73 ALOX15 (0.52) GRIK1GRIK2LMNAALOX15HSD17B10
SCHEMBL6130623 0.73 GRIK1 (0.38) GRIK1
SCHEMBL10937503 0.72 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL10937515 0.72 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3
SCHEMBL11802504 0.72 KDM4E (0.48) GRIK1GRIK2GRIA2GRIA4GRIK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952397-A CURABLE UPON EXPOSURE TO LIGHT INTO PRODUCT HAVING SHORE A HARDNESS OF 20 TO 60 AND LIGHT TRANSMITTANCE OF 10% AT WALL GAGE OF 10 MM; FOR FORMING TEMPLATING MOTHER MOLD WHICH ALLOWS RESIN CAST THEREIN TO BE CURED WITH LIGHT TRANSMITTED BY WALL SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-09-14 US disclosed
US-5474719-A Coating surface with layer of viscosity reduced photoformable material, allowing viscosity to increase, imagewise exposing to radiation, repeating until three-dimensional object is formed E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-12 US disclosed
EP-0403758-B1 Solid imaging method using compositions containing core-shell polymers DU PONT (US) 1995-07-05 EP disclosed
US-5364889-A Investment casting pattern material comprising thermally-collapsible expanded microspheres E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-11-15 US disclosed
US-5176188-A INVESTMENT CASTING METHOD AND PATTERN MATERIAL COMPRISING THERMALLY-COLLAPSIBLE EXPANDED MICROSPHERES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-05 US disclosed
EP-0403758-A2 Solid imaging method using compositions containing core-shell polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-12-27 EP disclosed