SCHEMBL6130623

SCHEMBL6130623

CC(O)C/C=C(/CC(C)O)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130626 1.00 GRIK1 (0.38) GRIK1
SCHEMBL31228875 0.83 GRIK1 (0.34) GRIK1
SCHEMBL10942638 0.81 GRIK1 (0.52) GRIK1
SCHEMBL2397901 0.77 GRIK1 (0.52) GRIK1
SCHEMBL2397898 0.77 GRIK1 (0.52) GRIK1
SCHEMBL445566 0.74 TDP1 (0.31)
SCHEMBL30808136 0.74 TDP1 (0.31)
SCHEMBL445565 0.74 TDP1 (0.31)
Acrylic Acid SCHEMBL8467600 0.73 GRIK1 (0.45) GRIK1
SCHEMBL7159680 0.69 CHRNB2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1451235-A4 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INT INC (US) 2005-06-22 EP disclosed
EP-1427694-A4 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INT INC (US) 2005-06-22 EP disclosed
US-6809216-B2 WATERPROOFING, OIL REPELLENTS, ANTISOILANTS HONEYWELL INTERNATIONAL INC. 2004-10-26 US disclosed
US-6800788-B2 FLUORINE-CONTAINING COMPOUNDS, AND POLYMERS DERIVED THEREFROM, FOR USE IN COMPOSITIONS USED FOR TREATING TEXTILE SUBSTRATES. ALSO PROVIDED ARE METHODS OF MAKING FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM, COMPOSITIONS HONEYWELL INTERNATIONAL INC. 2004-10-05 US disclosed
EP-1451235-A2 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International Inc. (US) 2004-09-01 EP disclosed
EP-1451228-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International, Inc. (US) 2004-09-01 EP disclosed
EP-1427694-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM Honeywell International Inc. (US) 2004-06-16 EP disclosed
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-06-12 US disclosed
US-20030092828-A1 Fluorine-containing compounds and polymers derived therefrom BRADLEY DAVID E (US) 2003-05-15 US disclosed
US-20030039919-A1 Fluorine-containing compounds and polymers derived therefrom HONEYWELL INTERNATIONAL INC. 2003-02-27 US disclosed
WO-2002103103-A2 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL INC. (US) 2002-12-27 WO disclosed
WO-2002102858-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL, INC. (US) 2002-12-27 WO disclosed
WO-2002102758-A1 FLUORINE-CONTAINING COMPOUNDS AND POLYMERS DERIVED THEREFROM HONEYWELL INTERNATIONAL, INC. (US) 2002-12-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030109626-A1 Fluorine-containing compounds and polymers derived therefrom WASF2, NOTUM, NEFM GRIK1 4218/4885
US-20030092828-A1 Fluorine-containing compounds and polymers derived therefrom WASF2, NOTUM, PFAS GRIK1 4119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.