Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493982 | 1.00 | SIGMAR1 (0.40) | SIGMAR1TMEM97EBPCTSKCTSS | |
| SCHEMBL25317343 | 0.81 | SIGMAR1 (0.38) | SIGMAR1TMEM97EBPPTGDR2PTGDR | |
| SCHEMBL29412738 | 0.78 | SIGMAR1 (0.56) | SIGMAR1TMEM97EBPSLC6A4CEL | |
| SCHEMBL7325355 | 0.78 | SIGMAR1 (0.56) | SIGMAR1TMEM97EBPSLC6A4CEL | |
| SCHEMBL26765552 | 0.77 | SIGMAR1 (0.44) | SIGMAR1TMEM97EBPSLC6A4 | |
| Hydrochloric Acid SCHEMBL9148670 | 0.77 | SIGMAR1 (0.55) | SIGMAR1TMEM97EBPCYP11B2 | |
| SCHEMBL8331479 | 0.77 | SIGMAR1 (0.39) | SIGMAR1TMEM97EBPPTGDR2PTGDR | |
| SCHEMBL26765546 | 0.76 | SIGMAR1 (0.43) | SIGMAR1TMEM97EBPSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL9151770 | 0.76 | SIGMAR1 (0.43) | SIGMAR1TMEM97EBPSLC6A4 | |
| Hydrochloric Acid SCHEMBL9319142 | 0.75 | SIGMAR1 (0.42) | SIGMAR1TMEM97EBPSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917464-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998004251-A1 | USE OF AMINES TO PRODUCE DRUGS FOR PREVENTING TUMOUR CELL PROLIFERATION | SANOFI (FR) | 1998-02-05 | — | — | WO | disclosed |