SCHEMBL25317343

SCHEMBL25317343

NCC#Cc1ccc(C2CCCCC2)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.38
TMEM97 Q5BJF2 1/20 0.38
EBP Q15125 1/20 0.38
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
THPO P40225 1/20 0.36
CEL P19835 2/20 0.36
NUDT1 P36639 1/20 0.35
BACE1 P56817 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
CYP11B2 P19099 1/20 0.33
PTGDR2 Q9Y5Y4 3/20 0.33
CYP2E1 P05181 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
PTGDR Q13258 2/20 0.32
PTGER2 P43116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26765546 0.81 SIGMAR1 (0.43) SIGMAR1TMEM97EBPCYP2C19CYP3A4
SCHEMBL8467835 0.81 SIGMAR1 (0.40) SIGMAR1TMEM97EBPCELCYP11B2
SCHEMBL30493982 0.81 SIGMAR1 (0.40) SIGMAR1TMEM97EBPCELCYP11B2
Hydrochloric Acid SCHEMBL9319142 0.80 SIGMAR1 (0.42) SIGMAR1TMEM97EBPCYP2C19CYP3A4
SCHEMBL26765552 0.79 SIGMAR1 (0.44) SIGMAR1TMEM97EBPHTR2AHTR2C
Hydrochloric Acid SCHEMBL9151770 0.78 SIGMAR1 (0.43) SIGMAR1TMEM97EBPCYP3A4HTR2A
SCHEMBL29412738 0.77 SIGMAR1 (0.56) SIGMAR1TMEM97EBPCYP1A2CYP2C19
SCHEMBL7325355 0.77 SIGMAR1 (0.56) SIGMAR1TMEM97EBPCYP1A2CYP2C19
SCHEMBL11246736 0.76 CEL (0.40) SIGMAR1TMEM97EBPCELCYP11B2
SCHEMBL11676061 0.76 CYP11B2 (0.50) SIGMAR1TMEM97EBPCELCYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1226825-A Use of amines to produce drugs for preventing tumour cell proliferation SANOFI SA (FR) 1999-08-25 CN claimed
EP-4213822-A1 COMPOUNDS FOR TREATING VIRUS INFECTIONS MELETIOS Therapeutics (FR) 2023-07-26 EP disclosed