Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5421055 | 1.00 | LMNA (0.59) | LMNAALOX15MTNR1AMTNR1BPPARG | |
| SCHEMBL9283760 | 1.00 | LMNA (0.59) | LMNAALOX15MTNR1AMTNR1BPPARG | |
| SCHEMBL2731803 | 1.00 | LMNA (0.59) | LMNAALOX15MTNR1AMTNR1BPPARG | |
| SCHEMBL7047542 | 0.89 | MAPT (0.51) | PPARGPPARAPKM | |
| SCHEMBL19132177 | 0.84 | TP53 (0.56) | LMNAALOX15PPARGPPARACYP2D6 | |
| SCHEMBL5512521 | 0.83 | LMNA (0.57) | LMNAALOX15MTNR1AMTNR1BPPARG | |
| SCHEMBL23827366 | 0.82 | TDP1 (0.44) | LMNAPPARGPPARAL3MBTL1ADRB2 | |
| SCHEMBL18990146 | 0.82 | LDHA (0.52) | LMNAKDM4E | |
| SCHEMBL23827362 | 0.82 | TDP1 (0.44) | LMNAPPARGPPARAL3MBTL1ADRB2 | |
| SCHEMBL11451793 | 0.82 | NR4A2 (0.47) | LMNAPPARGPPARAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886209-A | CATALYTIC ESTERIFICATION OF THE CHIRALIC CARBOXYLIC ACID IN PRESENCE OF A DISTILLABLE ACID CATALYST WITH AN ALCOHOL, WITHOUT PURIFICATION OF THE BOTTOMS PRODUCT, REPEATING THE ESTERIFICATION STEP | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |