SCHEMBL8468227

SCHEMBL8468227

CCS(=O)(=O)NS(N)(=O)=O

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 9/20 0.40
CA2 P00918 8/20 0.40
CA12 O43570 2/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.32
PPARA Q07869 1/20 0.30
CA4 P22748 1/20 0.30
CA5A P35218 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
HTT P42858 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL241832 0.79 CA1 (0.35) CA1CA2CA12CA14LMNA
SCHEMBL3897533 0.76 CA2 (0.48) CA1CA2CA12CA9CA14
SCHEMBL8468260 0.73 CA2 (0.52) CA1CA2CA9PPARA
SCHEMBL8469837 0.73 CA2 (0.52) CA1CA2CA9PPARA
SCHEMBL404551 0.71
SCHEMBL241512 0.71 CA2 (0.37) CA1CA2LMNAHPGDHTT
SCHEMBL17350952 0.69 PSIP1 (0.32) LMNAHPGDHTTSMN1; SMN2
SCHEMBL8468225 0.69 LMNA (0.30) LMNAHPGDHTTSMN1; SMN2
SCHEMBL6266852 0.67 CA2 (0.33) CA1CA2CA12CA9CA5A
SCHEMBL8468919 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107466296-A Imidazo [2,1 b] thiazole and 5,6 glyoxalidine as S100 inhibitor simultaneously [2,1 b] thiazole 活跃生物技术有限公司 2017-12-12 CN disclosed
EP-0756200-B1 Silver halide color photographic light-sensitive material KONISHIROKU PHOTO IND (JP) 1999-11-10 EP disclosed
US-5780215-A PAPER SUPPORT COATED ON SILVER EMULSION SIDE WITH TWO RESINS CONTAINING WHITE PIGMENT OF DIFFERING CONCENTRATIONS; CYAN COUPLERS; AGING RESISTANCE; GLOSS, DISCOLORATION INHIBITION OF THE WHITE BACKGROUND; COLORFASTNESS KONICA CORPORATION (JP) 1998-07-14 US disclosed
EP-0756200-A1 Silver halide color photographic light-sensitive material KONICA CORPORATION (JP) 1997-01-29 EP disclosed