Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3409848 | 0.85 | PPARA (0.46) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL8468153 | 0.85 | PPARA (0.46) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL11127080 | 0.81 | PPARA (0.50) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL8468475 | 0.80 | KCNN4 (0.50) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL11513416 | 0.80 | SRC (0.50) | PPARGL3MBTL1ATMKMT2AMAPT | |
| SCHEMBL28644949 | 0.80 | KCNN4 (0.50) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL27580615 | 0.79 | PDK1 (0.42) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL10654872 | 0.76 | PPARA (0.55) | PPARGPPARAMAPTCYP1A2CYP3A4 | |
| Bicarbonate SCHEMBL21635707 | 0.75 | ALDH1A1 (0.43) | PPARGL3MBTL1ATMPPARAKMT2A | |
| SCHEMBL675061 | 0.75 | CA4 (0.43) | PPARGL3MBTL1ATMPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646601-B1 | Motilin-like polypeptides with gastrointestinal motor stimulating activity | BAXTER INT (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0647656-B1 | Motilin-like polypeptides that inhibit gastrointestinal motor activity | BAXTER INT (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0807639-B1 | Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity | BAXTER PHARMACEUTICAL PRODUCTS (US) | 2000-02-09 | — | — | EP | disclosed |
| US-5734012-A | Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity | OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) | 1998-03-31 | — | — | US | disclosed |
| EP-0807639-A2 | Cyclic motilin-like polypeptides with gastrointestinal motor stimulating activity | Ohmeda Pharmaceutical Products Division Inc. (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5470830-A | Motilin-like polypeptides that inhibit gastrointestinal motor activity | OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) | 1995-11-28 | — | — | US | disclosed |
| US-5422341-A | Antidiabetic agents | OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) | 1995-06-06 | — | — | US | disclosed |
| EP-0647656-A1 | Motilin-like polypeptides that inhibit gastrointestinal motor activity | Ohmeda Pharmaceutical Products Division Inc. (US) | 1995-04-12 | — | — | EP | disclosed |
| EP-0646601-A1 | Motilin-like polypeptides with gastrointestinal motor stimulating activity | Ohmeda Pharmaceutical Products Division Inc. (US) | 1995-04-05 | — | — | EP | disclosed |