Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467070 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1CA2CA1MEN1 | |
| SCHEMBL8467034 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA2CA1MEN1 | |
| SCHEMBL8467037 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA2CA1MEN1 | |
| SCHEMBL8468116 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA2CA1MEN1 | |
| SCHEMBL8468115 | 0.93 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1CA2CA1MEN1 | |
| SCHEMBL8478495 | 0.80 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPK1FAAH | |
| SCHEMBL8478492 | 0.80 | KMT2A (0.46) | ALDH1A1MEN1KMT2AMAPK1FAAH | |
| SCHEMBL13417062 | 0.78 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL25418775 | 0.78 | FAAH (0.61) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL21142180 | 0.78 | FAAH (0.61) | ALDH1A1L3MBTL1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981580-A | IN WHICH THE CARBOXY-TERMINUS HAS BEEN MODIFIED TO FORM VARIOUS AMIDES, ESTERS, KETONES, ALCOHOLS, ALCOHOL ESTERS AND NITRITES THEREOF, AND ARE USEFUL AS SUBSTRATES FOR N-MYRISTOYLTRANSFERASE (NMT) AND/OR ITS ACYL COENZYME | G. D. SEARLE & CO. (US) | 1999-11-09 | — | — | US | disclosed |