Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 5/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12504703 | 0.80 | HTR7 (0.35) | HTR7ADRA1DADRA1AADRA1BCA1 | |
| SCHEMBL8523837 | 0.78 | SCN9A (0.31) | — | |
| SCHEMBL545236 | 0.78 | CA1 (0.37) | HTR7ADRA1DADRA1AADRA1BCA1 | |
| SCHEMBL4444984 | 0.74 | NPC1 (0.35) | HTR7ADRA1DADRA1AADRA1BCA1 | |
| SCHEMBL7108420 | 0.74 | HTR7 (0.33) | HTR7ADRA1DADRA1AADRA1BCDK1 | |
| SCHEMBL10940908 | 0.74 | CA1 (0.36) | HTR7ADRA1DADRA1AADRA1BCA1 | |
| Formaldehyde SCHEMBL5702331 | 0.73 | CA1 (0.38) | HTR7CA1CA2CA9 | |
| SCHEMBL8379018 | 0.71 | KCNH3 (0.35) | HTR7CA1CA2CA9 | |
| SCHEMBL8379029 | 0.71 | NPC1 (0.31) | — | |
| SCHEMBL8524744 | 0.71 | KCNH3 (0.50) | HTR7ADRA1DADRA1AADRA1BCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005056-A | REACTION PRODUCT OF EPOXY GROUP CONTAINING ACRYLIC COPOLYMERWITH A CARBOXYL GROUP CONTAINING POLYCYCLOALIPHATIC COMPOUND;CLEAR COATS FOR AUTOMOBILES; HIGH GLOSS | BOLLIG & KEMPER KG (DE) | 1999-12-21 | — | — | US | disclosed |