Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8379018 | 0.89 | KCNH3 (0.35) | CA1CA2CA9TLR8TLR7 | |
| SCHEMBL3981799 | 0.83 | CA1 (0.37) | CA1CA2CA9TLR8TLR7 | |
| SCHEMBL545236 | 0.82 | CA1 (0.37) | CA1CA2CA9GLANPC1 | |
| SCHEMBL3105245 | 0.82 | CA1 (0.39) | CA1CA2CA9GLANPC1 | |
| Formaldehyde SCHEMBL5702331 | 0.81 | CA1 (0.38) | CA1CA2CA9GLANPC1 | |
| SCHEMBL408240 | 0.80 | TLR8 (0.40) | CA1CA2CA9TLR8TLR7 | |
| SCHEMBL963512 | 0.79 | TLR8 (0.36) | CA1CA2CA9TLR8TLR7 | |
| SCHEMBL8524744 | 0.79 | KCNH3 (0.50) | CA1CA2CA9TLR8TLR7 | |
| SCHEMBL4444984 | 0.78 | NPC1 (0.35) | CA1CA2CA9GLANPC1 | |
| SCHEMBL11053521 | 0.77 | NOS1 (0.42) | TLR8TLR7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4515835-A | HYDROXY-FUNCTIONAL ADDITION POLYMER, REACTIVE DILUENT | ROHM AND HAAS COMPANY (US) | 1985-05-07 | — | — | US | disclosed |