Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9443881 | 0.84 | EPHX2 (0.46) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL10895418 | 0.83 | CTSL (0.55) | CA2CA12CA7CA14MEN1 | |
| SCHEMBL10895416 | 0.83 | CTSL (0.55) | CA2CA12CA7CA14MEN1 | |
| SCHEMBL10889192 | 0.83 | CTSL (0.55) | CA2CA12CA7CA14MEN1 | |
| SCHEMBL10887845 | 0.83 | CTSL (0.55) | CA2CA12CA7CA14MEN1 | |
| SCHEMBL11536650 | 0.77 | EPHX2 (0.39) | MEN1KMT2AHDAC8HDAC6EPHX2 | |
| SCHEMBL10884308 | 0.75 | EPHX2 (0.40) | MEN1KMT2AEPHX2MAPTCTSL | |
| SCHEMBL10884303 | 0.75 | HPGD (0.40) | EPHX2MAPTCTSLCTSSCTSK | |
| SCHEMBL10884310 | 0.75 | EPHX2 (0.40) | MEN1KMT2AEPHX2MAPTCTSL | |
| SCHEMBL8019409 | 0.74 | EPHX2 (0.49) | MEN1KMT2AHDAC8HDAC6EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659177-B1 | 4-OXO-AZETIDINE-2-SULPHONIC ACID AMIDES AND THEIR SALTS, PROCESS FOR THEIR PRODUCTION AND THEIR USE | PLIVA HANDELS GMBH (DE) | 1999-12-08 | — | — | EP | disclosed |
| US-5466686-A | Amides of 4-oxo-azetidine-2-sulfonic acids and salts thereof, processes for their preparation and their use | PLIVA AND PLIVA HANDELS GMBH (DE) | 1995-11-14 | — | — | US | disclosed |