Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847584 | 0.86 | LMNA (0.50) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL8467561 | 0.77 | TSHR (0.55) | LMNATSHRHPGDGAAALDH1A1 | |
| SCHEMBL869949 | 0.76 | LMNA (0.39) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL8467854 | 0.76 | LMNA (0.39) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL10873400 | 0.76 | HPGD (0.41) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL27900454 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL28910761 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL27289264 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL707305 | 0.75 | KCNH2 (0.47) | TSHRHPGDCA12ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL10815517 | 0.74 | CA12 (0.39) | CA12CA1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942470-A | OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| EP-0459656-B1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES INC (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0459656-A1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-12-04 | — | — | EP | disclosed |