Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469283 | 0.86 | LMNA (0.50) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL10867968 | 0.78 | NR1H2 (0.48) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL8467561 | 0.77 | TSHR (0.55) | LMNATSHRHPGDGAAALDH1A1 | |
| SCHEMBL869949 | 0.76 | LMNA (0.39) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL7240169 | 0.76 | MMP2 (0.55) | LMNATSHRCA12CA1MMP8 | |
| SCHEMBL8467854 | 0.76 | LMNA (0.39) | LMNATSHRHPGDCA12CA1 | |
| SCHEMBL10873400 | 0.76 | HPGD (0.41) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL28910761 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL27289264 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 | |
| P-Xylene SCHEMBL27900454 | 0.76 | LMNA (0.68) | LMNATSHRHPGDCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279765-B | A kind of fire retardant and preparation method thereof uses the copolyesters of the fire retardant and the preparation method of copolyesters and purposes | 东丽纤维研究所（中国）有限公司 | 2019-06-25 | — | — | CN | disclosed |
| CN-108774260-A | A kind of synthetic method of group thiophosphate compound | 广东工业大学 | 2018-11-09 | — | — | CN | disclosed |
| CN-106279765-A | A kind of fire retardant and preparation method thereof, use the copolyesters of this fire retardant and the preparation method of copolyesters and purposes | 东丽纤维研究所（中国）有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-105985514-A | Preparation method of flame-retardant polyester composition | 东丽纤维研究所（中国）有限公司 | 2016-10-05 | — | — | CN | disclosed |
| US-7022833-B2 | Process for the preparation of phosphorothioate triesters | AVECIA LIMITED (GB) | 2006-04-04 | — | — | US | disclosed |
| US-7019127-B2 | Solution phase synthesis of oligonucleotides | AVECIA LIMITED (GB) | 2006-03-28 | — | — | US | disclosed |
| US-20050240015-A1 | Solution phase synthesis of oligonucleotides | AVECIA LIMITED (GB) | 2005-10-27 | — | — | US | disclosed |
| EP-1272501-B1 | PROCESS FOR THE PREPARATION OF PHOSPHOROTHIOATE TRIESTERS | AVECIA LTD (GB) | 2004-05-06 | — | — | EP | disclosed |
| EP-1325927-A2 | Synthesis of oligonucleotides | Avecia Limited (GB) | 2003-07-09 | — | — | EP | disclosed |
| WO-2003045969-A1 | COUPLING REAGENT FOR H-PHOSPHONATE CHEMISTRY | AVECIA BIOTECHNOLOGY INC. (US) | 2003-06-05 | — | — | WO | disclosed |
| US-5942470-A | OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1999009041-A2 | SOLUTION PHASE SYNTHESIS OF OLIGONUCLEOTIDES | AVECIA LIMITED (GB) | 1999-02-25 | — | — | WO | disclosed |
| EP-0531585-B1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LTD (GB) | 1998-11-04 | — | — | EP | disclosed |
| US-5464549-A | Oil soluble dispersants suitable for use in fuels and lubricants | ETHYL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0459656-B1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES INC (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5358652-A | Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound | ETHYL PETROLEUM ADDITIVES, LIMITED (GB) | 1994-10-25 | — | — | US | disclosed |
| US-5241003-A | Post-treated polyisobutenyl succinimide; crankcase, transmission oils | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0531585-A1 | Oil additive concentrates and lubricants of enhanced performance capabilities | ETHYL PETROLEUM ADDITIVES LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |
| US-5137980-A | Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1992-08-11 | — | — | US | disclosed |
| EP-0459656-A1 | Lubricant compositions | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-12-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050240015-A1 | Solution phase synthesis of oligonucleotides | NUDT1, POLR2E, POLRMT | LMNA 3061/4885TSHR 1672/4885HPGD 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.