SCHEMBL707305

SCHEMBL707305

O=P(O)(Sc1ccccc1)Sc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA5A P35218 1/20 0.46
HPGD P15428 2/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MGLL Q99685 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SRC P12931 2/20 0.41
CFTR P13569 1/20 0.41
PTPN1 P18031 1/20 0.39
FFAR1 O14842 1/20 0.39
TSHR P16473 2/20 0.38
ALOX15 P16050 1/20 0.38
ALDH1A1 P00352 3/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10808794 0.85 MMP2 (0.47) KCNH2HPGDMAPTHSD17B10TSHR
SCHEMBL108542 0.84 KCNH2 (0.47) KCNH2CA2CA4CA5AHPGD
Hydrochloric Acid SCHEMBL4656192 0.82 KCNH2 (0.45) KCNH2CA2CA4CA5AHPGD
SCHEMBL5351835 0.80 KCNH2 (0.44) KCNH2CA2CA4CA5AHPGD
Cyclohexylamine SCHEMBL6623333 0.80 ALDH1A1 (0.38) KCNH2CA2CA4CA5AHPGD
SCHEMBL2502560 0.79 KCNH2 (0.47) KCNH2CA2CA4CA5AHPGD
SCHEMBL6831537 0.78 CA2 (0.52) KCNH2CA2CA4CA5AHPGD
SCHEMBL11642515 0.78 KCNH2 (0.40) KCNH2CA2CA4CA5AHPGD
SCHEMBL1883203 0.78 KCNH2 (0.61) KCNH2CA2CA4CA5AHPGD
SCHEMBL3056851 0.77 KCNH2 (0.46) KCNH2CA2CA4CA5AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094087-B1 PESTICIDAL COMPOSITIONS ISHIHARA SANGYO KAISHA (JP) 2016-08-24 EP claimed
US-20040142946-A1 Modified nucleosides and nucleotides and use thereof CHATTOPADHYAYA JYOTI (SE) 2004-07-22 US claimed
EP-1332150-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF Chattopadhyaya, Jyoti (SE) 2003-08-06 EP claimed
WO-2002038578-A1 MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF CHATTOPADHYAYA JYOTI (SE) 2002-05-16 WO claimed
US-5721350-A Deuterated nucleosides CHATTOPADHYAYA JYOTI (SE) 1998-02-24 US claimed
WO-1993025566-A1 DEUTERATED NUCLEOSIDES CHATTOPADHYAYA JYOTI (SE) 1993-12-23 WO claimed
US-4731385-A NITROMETHYLENE DERIVATIVE NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1988-03-15 US claimed
JP-6184375-A None JP disclosed
CN-111032837-B Gear oil composition for automobile and lubricating method 出光兴产株式会社 2023-03-31 CN disclosed
CN-110330526-B Green synthesis method of thiophosphite 成都理工大学 2021-11-26 CN disclosed
CN-111032837-A Gear oil composition for automobile and lubricating method 出光兴产株式会社 2020-04-17 CN disclosed
US-10472525-B2 Use of dithiophosphinic acid and/or its salts for producing anti-corrosion coatings that are devoid of chrome BASF COATINGS GMBH (DE) 2019-11-12 US disclosed
EP-2306831-B1 PESTICIDAL COMPOSITION ISHIHARA SANGYO KAISHA (JP) 2018-03-28 EP disclosed
US-4617584-A GOOD HUMIDITY RESISTANCE, CORROSION RESITANCE; CURED NOVOLAC TYPE EPOXY RESIN, NOVOLAC PHENOLIC RESIN AND ORGANIC PHOSPHOROUS COMPOUND TOKYO SHIBAURA DENKI KABUSHIKI KAISHA (JP) 1986-10-14 US disclosed
EP-0013744-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION OF ALPHA-OLEFINS AND A PROCESS FOR PREPARING AN ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT Standard Oil Company (US) 1984-11-07 EP disclosed
EP-0120981-A1 Resin encapsulation type semiconductor device KABUSHIKI KAISHA TOSHIBA (JP) 1984-10-10 EP disclosed
US-4353916-A Benzothiazol-2-ones and phytopathogenic fungicidal use thereof SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1982-10-12 US disclosed
US-4233182-A High activity catalyst for the polymerization of alpha-olefins STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
US-4233253-A Method for the preparation of metal salts of phosphorus acid esters STANDARD OIL COMPANY (INDIANA) (US) 1980-11-11 US disclosed
EP-0013744-A1 Catalyst and process for the polymerization of alpha-olefins and a process for preparing an alpha-olefin polymerization catalyst component Standard Oil Company (US) 1980-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142946-A1 Modified nucleosides and nucleotides and use thereof RNASEH1, RNASEL, NSUN2 KCNH2 536/4885CA2 2368/4885CA4 2059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.