Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469298 | 0.85 | KMT2A (0.48) | KMT2AOPRM1CA1CA2CA7 | |
| SCHEMBL3870396 | 0.85 | PPARD (0.52) | KMT2AOPRM1CA1CA2CA7 | |
| SCHEMBL8327308 | 0.85 | KMT2A (0.45) | KMT2AOPRM1CA1CA2CA7 | |
| SCHEMBL8466120 | 0.83 | KMT2A (0.47) | KMT2AOPRM1OPRK1 | |
| SCHEMBL9582419 | 0.83 | OPRM1 (0.51) | KMT2AOPRM1CA1CA2CA7 | |
| SCHEMBL3382275 | 0.83 | KMT2A (0.62) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3383043 | 0.83 | KMT2A (0.62) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7334819 | 0.81 | SMN1; SMN2 (0.57) | KMT2AOPRM1OPRK1 | |
| SCHEMBL10516146 | 0.81 | KMT2A (0.48) | KMT2AOPRM1CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL8470673 | 0.80 | SMN1; SMN2 (0.56) | KMT2AOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |