Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398371 | 1.00 | REN (0.37) | RENTDP1TACR1LTA4HSIGMAR1 | |
| SCHEMBL8399929 | 0.96 | REN (0.39) | RENTDP1TACR1SMN1; SMN2HTT | |
| SCHEMBL8469404 | 0.92 | LTA4H (0.40) | TDP1TACR1LTA4HSIGMAR1HTT | |
| SCHEMBL8831280 | 0.92 | PDPK1 (0.36) | TACR1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8831054 | 0.92 | PDPK1 (0.36) | TACR1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9058173 | 0.92 | PDPK1 (0.36) | TACR1NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8398131 | 0.91 | SLC5A1 (0.38) | RENTDP1TACR1SMN1; SMN2HTT | |
| SCHEMBL8397734 | 0.89 | SSTR5 (0.33) | TDP1TACR1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL584139 | 0.84 | PDPK1 (0.40) | TACR1 | |
| SCHEMBL13858947 | 0.84 | PDPK1 (0.40) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874411-A | ANTIINFLAMMATORY | GLYCOMED INCORPORATED (US) | 1999-02-23 | — | — | US | disclosed |