SCHEMBL8469411

SCHEMBL8469411

CCCCCCCCCCCCCC(CCC1(C(=O)O)CCO1)CC(O)CO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.38
GPR84 Q9NQS5 7/20 0.37
FFAR1 O14842 2/20 0.36
FFAR4 Q5NUL3 1/20 0.36
KDM4E B2RXH2 2/20 0.36
DUSP3 P51452 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2D6 P10635 2/20 0.34
SPHK1 Q9NYA1 1/20 0.34
GMNN O75496 1/20 0.34
POLB P06746 1/20 0.34
THPO P40225 1/20 0.34
MTOR P42345 1/20 0.34
BLM P54132 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
MAPT P10636 1/20 0.34
CETP P11597 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8667713 0.95 LMNA (0.38) LMNAGPR84FFAR1FFAR4KDM4E
SCHEMBL8520442 0.95 LMNA (0.38) LMNAGPR84FFAR1FFAR4KDM4E
SCHEMBL1325116 0.90 LMNA (0.32) LMNAGPR84FFAR1FFAR4
SCHEMBL1323910 0.84 FFAR1 (0.36) FFAR1FFAR4CYP2D6TP53CYP1A2
SCHEMBL15392560 0.80 FFAR1 (0.50) GPR84FFAR1FFAR4
SCHEMBL16500283 0.77 GPR84 (0.39) LMNAGPR84FFAR1FFAR4KDM4E
SCHEMBL14672700 0.77 GPR84 (0.39) LMNAGPR84FFAR1FFAR4KDM4E
SCHEMBL8519329 0.77 ACACB (0.34) GPR84FFAR1FFAR4CYP3A4
SCHEMBL3260514 0.76 ALDH1A1 (0.38) GPR84
SCHEMBL24919805 0.76 LMNA (0.64) LMNAGPR84FFAR1FFAR4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0633019-B1 Pressurized gas packagings using polyoxyethylene glyceryl fatty acid esters as suspension stabilizers and valve lubricants ASTA MEDICA AG (DE) 1999-08-11 EP claimed
CN-1075722-C Fungicidal compositions containing bifonazole AGIS IND 1983 LTD (IL) 2001-12-05 CN disclosed
US-5869529-A ADMINISTERING A TOPICAL COMPOSITION CONSISTING ESSENTIALLY OF AN ALKALI OLEATE AGIS INDUSTRIES (1983) LTD. (IL) 1999-02-09 US disclosed
EP-0676198-B1 Fungicidal compositions containing a combination of bifonazole and fluocinonide AGIS IND 1983 LTD (IL) 1998-10-07 EP disclosed
EP-0787490-A1 A topical preparation for the prevention and treatment of lesions and sores associated with a herpes virus AGIS INDUSTRIES (1983) LTD (IL) 1997-08-06 EP disclosed
WO-1996002244-A1 A TOPICAL PREPARATION FOR THE PREVENTION AND TREATMENT OF LESIONS AND SORES ASSOCIATED WITH A HERPES VIRUS AGIS INDUSTRIES (1983) LTD. (IL) 1996-02-01 WO disclosed
CN-1111513-A Fungicidal compositions containing bifonazole AGIS IND 1983 LTD (IL) 1995-11-15 CN disclosed