Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8469605

CC1CCCCC1(C)OC(=O)c1ccccc1.N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
SCN1A P35498 2/20 0.39
SCN2A Q99250 2/20 0.39
SCN3A Q9NY46 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.39
TSHR P16473 1/20 0.39
CYP19A1 P11511 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNA5 P30532 1/20 0.37
CHRNA7 P36544 1/20 0.37
CHRNA4 P43681 1/20 0.37
F2 P00734 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6900836 0.91 MAPT (0.39) GAACYP1A2CYP2D6MEN1KMT2A
SCHEMBL11763859 0.89 RXRA (0.38) KMT2ATSHR
SCHEMBL1685334 0.85 CYP3A4 (0.39) LMNATDP1SCN1ASCN2ASCN3A
SCHEMBL1685335 0.83 CYP3A4 (0.47) TDP1SCN1ASCN2ASCN3ACYP2D6
SCHEMBL11494838 0.82 SMN1; SMN2 (0.35) MEN1KMT2ACYP19A1
SCHEMBL11126179 0.77 KMT2A (0.40) GAALMNATDP1SCN1ASCN2A
SCHEMBL27896935 0.76 ALOX15 (0.34) LMNACYP1A2TSHR
SCHEMBL13561708 0.75 TSHR (0.48) GAALMNATDP1SCN1ASCN2A
SCHEMBL13564220 0.73 TSHR (0.47) GAALMNATDP1SCN1ASCN2A
SCHEMBL27347701 0.73 LMNA (0.35) GAALMNATDP1SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0531585-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LTD (GB) 1998-11-04 EP disclosed
EP-0531000-B1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES INC (US) 1997-02-05 EP disclosed
US-5464549-A Oil soluble dispersants suitable for use in fuels and lubricants ETHYL CORPORATION (US) 1995-11-07 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
US-5358652-A Using 3,5-dihydrocarbyl-4-hydroxybenzylamine compound ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1994-10-25 US disclosed
EP-0428393-B1 GEAR OILS AND ADDITIVES THEREFOR ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-10-06 EP disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
EP-0531585-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-03-17 EP disclosed
EP-0531000-A1 Oil additive concentrates and lubricants of enhanced performance capabilities ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-03-10 EP disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed
EP-0430624-A1 Gear oils and additives therefor ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-06-05 EP disclosed
EP-0428393-A1 Gear oils and additives therefor ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-05-22 EP disclosed