Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468791 | 0.86 | PPARG (0.45) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6958646 | 0.82 | PPARG (0.42) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL8524260 | 0.80 | MAPT (0.46) | PPARAALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6966942 | 0.79 | PPARG (0.38) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL4747685 | 0.78 | FFAR1 (0.52) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6956424 | 0.75 | PPARG (0.40) | PPARGPPARAALDH1A1LMNAMAPT | |
| SCHEMBL8468559 | 0.73 | LMNA (0.36) | LMNA | |
| SCHEMBL4744208 | 0.73 | PPARG (0.59) | PPARGPPARAHRH3FFAR1 | |
| SCHEMBL6966158 | 0.72 | PPARA (0.41) | PPARGPPARAFFAR1 | |
| SCHEMBL6964328 | 0.72 | FFAR1 (0.41) | PPARGPPARAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009980-A1 | METHOD FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |