Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | ATP4A | P20648 | 6/20 | 0.39 |
| ▸ | ATP4B | P51164 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954172 | 0.82 | SMN1; SMN2 (0.41) | MAPTTP53SMN1; SMN2PPARDPPARA | |
| SCHEMBL8469663 | 0.80 | PPARG (0.43) | MAPTSMN1; SMN2PPARAALDH1A1LMNA | |
| SCHEMBL9005970 | 0.78 | PTPN2 (0.47) | MAPTTP53SMN1; SMN2ATP4AATP4B | |
| SCHEMBL6964861 | 0.74 | CNR2 (0.39) | MAPTTP53PPARDPPARA | |
| SCHEMBL1856421 | 0.71 | RAB9A (0.43) | MAPTTP53SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL16297363 | 0.70 | ATP4A (0.61) | MAPTATP4AATP4BRAB9A | |
| SCHEMBL510500 | 0.69 | ALDH1A1 (0.73) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6960978 | 0.68 | TP53 (0.42) | MAPTTP53SMN1; SMN2PPARDPPARA | |
| SCHEMBL3077169 | 0.67 | ALDH1A1 (0.67) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL8468791 | 0.67 | PPARG (0.45) | SMN1; SMN2PPARAALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999009980-A1 | METHOD FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 1999-03-04 | — | — | WO | disclosed |