Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355500 | 0.82 | ALDH1A1 (0.43) | CA1CA2CA9CA12CA14 | |
| SCHEMBL27622144 | 0.80 | CA1 (0.51) | CA1CA2ACHEPKMACP3 | |
| Sulfuric Acid SCHEMBL22498737 | 0.80 | CA1 (0.51) | CA1CA2ACHEPKMAOC3 | |
| SCHEMBL27763142 | 0.78 | CA1 (0.46) | CA1CA2ACHEPKMAOC3 | |
| SCHEMBL2388659 | 0.78 | CA1 (0.50) | CA1CA2ACHEPKMAOC3 | |
| SCHEMBL11218212 | 0.78 | ALOX5 (0.49) | CA1CA2ACHEPKMMMP13 | |
| SCHEMBL14355490 | 0.78 | L3MBTL1 (0.53) | AOC3ALDH1A1TSHRMAPK1L3MBTL1 | |
| SCHEMBL18608218 | 0.77 | ACACB (0.47) | CA1CA2CA9CA12ALDH1A1 | |
| SCHEMBL10404138 | 0.76 | CA1 (0.44) | CA1CA2ACHEPKMACP3 | |
| SCHEMBL10402675 | 0.76 | CA1 (0.44) | CA1CA2ACHEPKMACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0956282-A1 | SULPHINIC ACID DERIVATIVES, METHOD FOR PRODUCING THEM, AND THEIR USE | L. Brüggemann KG (DE) | 1999-11-17 | — | — | EP | claimed |
| WO-1999018067-A1 | SULPHINIC ACID DERIVATIVES, METHOD FOR PRODUCING THEM, AND THEIR USE | L. Brüggemann KG (DE) | 1999-04-15 | — | — | WO | claimed |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | MANI NEELAKANDHA S (US) | 2012-11-08 | — | — | US | disclosed |
| US-20120029191-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | MANI NEELAKANDHA S (US) | 2012-02-02 | — | — | US | disclosed |
| US-8063206-B2 | Processes for the preparation of cyclopropyl-amide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-22 | — | — | US | disclosed |
| US-20100286391-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-11-11 | — | — | US | disclosed |
| US-7795426-B2 | Processes for the preparation of cyclopropyl-amide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2010-09-14 | — | — | US | disclosed |
| US-20100197689-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2010-08-05 | — | — | US | disclosed |
| US-7728129-B2 | Processes for the preparation of piperazinyl and diazapanyl benzamide derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2010-06-01 | — | — | US | disclosed |
| US-7300501-B2 | Electroless gold plating liquid | NIKKO MATERIALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7300501-B2 | Electroless gold plating liquid | NIKKO MATERIALS CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-08-23 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-06-07 | — | — | US | disclosed |
| WO-2007053386-A2 | PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007053427-A2 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-05-10 | — | — | WO | disclosed |
| US-20070095249-A1 | Electroless gold plating liquid | JX NIPPON MINING & METALS CORPORATION (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20070095249-A1 | Electroless gold plating liquid | JX NIPPON MINING & METALS CORPORATION (JP) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286391-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | CA1 1662/4885CA2 1679/4885ACHE 903/4885 |
| US-20070197508-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | HRH2, HRH4, HRH1 | CA1 2497/4885CA2 1016/4885ACHE 758/4885 |
| US-20100197689-A1 | NOVEL PROCESSES FOR THE PREPARATION OF PIPERAZINYL AND DIAZAPANYL BENZAMIDE DERIVATIVES | HRH2, HRH4, HRH1 | CA1 2497/4885CA2 1016/4885ACHE 758/4885 |
| US-20070129351-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | CA1 1662/4885CA2 1679/4885ACHE 903/4885 |
| US-20120283433-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | CA1 1662/4885CA2 1679/4885ACHE 903/4885 |
| US-20120029191-A1 | NOVEL PROCESSES FOR THE PREPARATION OF CYCLOPROPYL-AMIDE DERIVATIVES | HRH4, HRH2, HRH1 | CA1 1662/4885CA2 1679/4885ACHE 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.