Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712951 | 0.81 | MAOA (0.42) | MAOAMAOBESR1TSHRALDH1A1 | |
| SCHEMBL7712985 | 0.81 | MAOA (0.42) | MAOAMAOBESR1TSHRALDH1A1 | |
| SCHEMBL9303185 | 0.80 | ESR1 (0.55) | ESR1TSHRTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2426331 | 0.78 | TSHR (0.54) | TSHRTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL16680262 | 0.77 | ACE (0.51) | — | |
| SCHEMBL7706678 | 0.76 | KDM6B (0.46) | MAOAMAOBTDP1ALDH1A1RIPK1 | |
| SCHEMBL7707907 | 0.76 | KDM6B (0.46) | MAOAMAOBTDP1ALDH1A1RIPK1 | |
| SCHEMBL14532665 | 0.75 | LMNA (0.51) | L3MBTL1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL7711037 | 0.74 | KDM6B (0.61) | MAOAMAOBRIPK1 | |
| SCHEMBL7230282 | 0.74 | KDM6B (0.61) | MAOAMAOBRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |