Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | GAPDH | P04406 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469479 | 0.93 | LMNA (0.65) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL26009136 | 0.91 | LMNA (0.59) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL4607313 | 0.91 | LMNA (0.71) | LMNAGAAMAPTTDP1GAPDH | |
| SCHEMBL8678710 | 0.90 | ABL1 (0.59) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL28032593 | 0.89 | LMNA (0.66) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL4446422 | 0.86 | MAPT (0.67) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL8523753 | 0.85 | CYP3A4 (0.66) | LMNAGAAMAPTTDP1ABL1 | |
| SCHEMBL28743154 | 0.85 | LMNA (0.66) | LMNAGAAMAPTTDP1GAPDH | |
| SCHEMBL2608606 | 0.84 | HSD17B10 (0.66) | LMNAGAABACE1MAPTTDP1 | |
| SCHEMBL14700512 | 0.84 | HSD17B10 (0.66) | LMNAGAABACE1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025707-A1 | 2-ARYLBENZO[b]THIOPHENES USEFUL FOR THE TREATMENT OF ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |