SCHEMBL26009136

SCHEMBL26009136

COc1cccc(-c2cccc(OC(C)=O)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
CYP3A4 P08684 2/20 0.59
GAPDH P04406 2/20 0.59
NPC1 O15118 1/20 0.57
ALDH1A1 P00352 1/20 0.57
TP53 P04637 1/20 0.57
HTT P42858 1/20 0.57
RAB9A P51151 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
HDAC4 P56524 1/20 0.57
HDAC8 Q9BY41 1/20 0.57
ACHE P22303 1/20 0.54
GAA P10253 1/20 0.53
BACE1 P56817 1/20 0.53
MAPT P10636 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CYP1A1 P04798 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2E1 P05181 1/20 0.52
CYP2C8 P10632 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469858 0.91 LMNA (0.60) LMNACYP3A4GAPDHALDH1A1SMN1; SMN2
SCHEMBL8469479 0.91 LMNA (0.65) LMNAGAPDHHDAC4HDAC8GAA
SCHEMBL28032593 0.90 LMNA (0.66) LMNACYP3A4GAPDHALDH1A1ACHE
SCHEMBL361383 0.90 LMNA (0.66) LMNACYP3A4GAPDHNPC1ALDH1A1
SCHEMBL8218800 0.89 LMNA (0.63) LMNACYP3A4GAPDHNPC1ALDH1A1
SCHEMBL4446422 0.87 MAPT (0.67) LMNACYP3A4ALDH1A1ACHEGAA
SCHEMBL4607313 0.85 LMNA (0.71) LMNACYP3A4GAPDHACHEGAA
SCHEMBL26009141 0.85 MTNR1B (0.59) LMNACYP3A4GAPDHNPC1ALDH1A1
Acetic Acid SCHEMBL28960935 0.85 HDAC4 (0.61) LMNACYP3A4ALDH1A1HDAC4HDAC8
SCHEMBL8264641 0.84 LMNA (0.79) LMNACYP3A4GAPDHALDH1A1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230266684-A1 IMAGE FORMING UNIT AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed
US-20230266683-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-08-24 US disclosed