SCHEMBL8470484

SCHEMBL8470484

O=[N+]([O-])c1ccc2c(c1)OCN2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SNCA P37840 4/20 0.43
CAPN9 O14815 1/20 0.42
CASP3 P42574 1/20 0.42
ALDH1A1 P00352 4/20 0.41
POLB P06746 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.40
CA9 Q16790 1/20 0.40
NR3C1 P04150 1/20 0.40
PGR P06401 1/20 0.40
AR P10275 1/20 0.40
LMNA P02545 2/20 0.39
TSHR P16473 2/20 0.39
NOS1 P29475 2/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2721900 0.86 MAPT (0.48) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL303351 0.83 MEN1 (0.46) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL31021147 0.83 MEN1 (0.46) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL2061792 0.81 MEN1 (0.44) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL27701186 0.77 CAPN9 (0.41) MAPTMEN1KMT2ASNCACAPN9
SCHEMBL282326 0.76 POLB (0.51) MAPTMEN1KMT2ACAPN9CASP3
SCHEMBL30806805 0.76 POLB (0.51) MAPTMEN1KMT2ACAPN9CASP3
SCHEMBL4577576 0.74 NR3C1 (0.48) MAPTMEN1KMT2ASNCACAPN9
SCHEMBL9143251 0.74 MAPT (0.50) MAPTMEN1KMT2ANPC1RAB9A
SCHEMBL5522362 0.73 ALDH1A1 (0.46) MAPTMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed