Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469517 | 1.00 | MAPT (0.41) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL8469615 | 0.84 | POLB (0.42) | MAPTABL1RIN1POLBTSHR | |
| SCHEMBL8470363 | 0.84 | POLB (0.42) | MAPTABL1RIN1POLBTSHR | |
| SCHEMBL12671946 | 0.81 | ABL1 (0.43) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL8469822 | 0.79 | ABL1 (0.41) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL9034422 | 0.79 | ABL1 (0.41) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL9530859 | 0.78 | LMNA (0.57) | MAPTPOLBLMNACACNA1FALB | |
| SCHEMBL14581404 | 0.76 | ALB (0.65) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL5430795 | 0.76 | ALB (0.65) | MAPTABL1RIN1POLBLMNA | |
| SCHEMBL31289523 | 0.76 | ALB (0.65) | MAPTABL1RIN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2960164-B2 | — | — | 1999-10-06 | — | — | JP | claimed |
| EP-0236931-B1 | Aromatic omega-alkylimino-tetrahydro-6H-1,3-Thiazin-6-one derivatives | MERRELL DOW PHARMA (US) | 1993-12-29 | — | — | EP | claimed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | claimed |
| WO-1992008717-A1 | SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES | BIOCHEM PHARMA INC. (CA) | 1992-05-29 | — | — | WO | disclosed |