SCHEMBL8470853

SCHEMBL8470853

COCOC[C@H]1O[C@@H](n2cc(C)c(=O)[nH]c2=O)C[C@@H]1O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.64
POLB P06746 1/20 0.63
TYMS P04818 1/20 0.56
BCHE P06276 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22943603 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL522285 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17236294 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL135209 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL17232081 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL12918450 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL4198253 0.91 TK1 (0.69) TK1POLBTYMSBCHE
SCHEMBL888318 0.90 POLB (0.65) TK1POLBTYMS
SCHEMBL4422933 0.89 POLB (0.66) TK1POLBTYMS
SCHEMBL16359946 0.89 TK1 (0.69) TK1POLBTYMSBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0789706-A4 SUGAR MODIFIED NUCLEOSIDES AND THEIR USE FOR SYNTHESIS OF OLIGONUCLEOTIDES ICN PHARMACEUTICALS (US) 1999-08-11 EP disclosed
EP-0789706-A1 SUGAR MODIFIED NUCLEOSIDES AND THEIR USE FOR SYNTHESIS OF OLIGONUCLEOTIDES ICN PHARMACEUTICALS (US) 1997-08-20 EP disclosed
WO-1996014329-A1 SUGAR MODIFIED NUCLEOSIDES AND THEIR USE FOR SYNTHESIS OF OLIGONUCLEOTIDES ICN PHARMACEUTICALS (US) 1996-05-17 WO disclosed