Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | RGS12 | O14924 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4804043 | 0.82 | NPC1 (0.57) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL5709299 | 0.79 | CHRM2 (0.61) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL9299531 | 0.79 | CHRM2 (0.61) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL5700232 | 0.79 | CHRM2 (0.61) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL8470684 | 0.79 | CHRM2 (0.53) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL16164987 | 0.77 | ADRA2C (0.62) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL15271619 | 0.76 | MEN1 (0.51) | KMT2AMEN1TDP1HSD17B10GLA | |
| SCHEMBL8470500 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL14393865 | 0.75 | ADRA2C (0.60) | KMT2AMEN1TDP1HSD17B10TSHR | |
| SCHEMBL4407404 | 0.75 | ADRA2C (0.60) | KMT2AMEN1TDP1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998624-A | MEDICAL DIAGNOSIS; BINDING TO SITE OF INJURY, INFLAMMATION | EMORY UNIVERSITY (US) | 1999-12-07 | — | — | US | disclosed |
| WO-1998049900-A1 | HALOISOQUINOLINE CARBOXAMIDE | EMORY UNIVERSITY (US) | 1998-11-12 | — | — | WO | disclosed |