Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | C1R | P00736 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074295 | 0.88 | MAPT (0.40) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL8469903 | 0.88 | LMNA (0.40) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL8469910 | 0.85 | LMNA (0.38) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL8470361 | 0.84 | LMNA (0.41) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| Bromide SCHEMBL8469205 | 0.82 | TP53 (0.52) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL8136893 | 0.81 | TP53 (0.49) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL8469584 | 0.81 | MAPT (0.53) | TP53LMNAMAPTKDM4EHSP90AA1 | |
| SCHEMBL9407935 | 0.81 | GAA (0.36) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL9407899 | 0.79 | ALDH1A1 (0.43) | TP53LMNAMAPTHSP90AA1ALDH1A1 | |
| SCHEMBL8144928 | 0.79 | TP53 (0.64) | TP53LMNAMAPTHSP90AA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |