Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074295 | 0.94 | MAPT (0.40) | GAAMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9407899 | 0.92 | ALDH1A1 (0.43) | GAAMAPTALDH1A1KMT2AF2 | |
| SCHEMBL9407963 | 0.83 | MAPT (0.43) | GAAMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10691854 | 0.83 | TAS2R14 (0.41) | ALDH1A1KMT2AMEN1 | |
| Bromide SCHEMBL7464567 | 0.82 | TAS2R14 (0.40) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL8470965 | 0.81 | TP53 (0.44) | GAAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7458558 | 0.80 | MAPT (0.45) | GAAMAPK1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8079566 | 0.80 | LMNA (0.37) | GAAMAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8074300 | 0.78 | ALDH1A1 (0.40) | GAAMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL9407932 | 0.77 | LMNA (0.35) | GAAMAPTSMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0602524-A1 | Chemiluminescence marked sequences and their use in sequence testing | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |