SCHEMBL8471302

SCHEMBL8471302

CCC=CCCC(CC)c1cccc2[nH]c(=O)n(CC)c12

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PGR P06401 1/20 0.33
DAO P14920 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR1A P08908 8/20 0.31
DRD2 P14416 3/20 0.31
DRD3 P35462 3/20 0.31
MAOB P27338 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8471574 0.91 CYP1A2 (0.41) CYP1A2MEN1KMT2APGRDAO
SCHEMBL8475342 0.84 CYP1A2 (0.39) CYP1A2MEN1KMT2APGRDAO
SCHEMBL8471506 0.82 CYP1A2 (0.43) CYP1A2MEN1KMT2APGRDAO
SCHEMBL3746600 0.74 CYP1A2 (0.39) CYP1A2MEN1KMT2ADAOLMNA
SCHEMBL3207595 0.72 KDM4E (0.39) CYP1A2MEN1KMT2ADAOSMN1; SMN2
SCHEMBL3202684 0.71 MPO (0.44) CYP1A2MEN1KMT2AHTR1ADRD2
SCHEMBL2084761 0.70 ADORA3 (0.42) CYP1A2MEN1KMT2APGRDAO
SCHEMBL8471592 0.68 KDM4E (0.36) MEN1KMT2APGRLMNASMN1; SMN2
SCHEMBL3210120 0.67 KDM4E (0.49) MEN1KMT2ALMNATSHRSMN1; SMN2
SCHEMBL24608420 0.67 CYP1A2 (0.56) CYP1A2MEN1KMT2APGRDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5908844-A N-substituted azabicycloalkane derivatives, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1999-06-01 US disclosed