Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 5/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD3 | P35462 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471574 | 0.93 | CYP1A2 (0.41) | CYP1A2MEN1KMT2APGRDAO | |
| SCHEMBL8471506 | 0.85 | CYP1A2 (0.43) | CYP1A2MEN1KMT2APGRDAO | |
| SCHEMBL8471302 | 0.84 | CYP1A2 (0.41) | CYP1A2MEN1KMT2APGRDAO | |
| SCHEMBL30627214 | 0.72 | PLAT (0.39) | DAOHTR1ALMNACYP2D6DRD2 | |
| SCHEMBL3746600 | 0.72 | CYP1A2 (0.39) | CYP1A2MEN1KMT2ADAOHTR1A | |
| SCHEMBL3207595 | 0.70 | KDM4E (0.39) | CYP1A2MEN1KMT2ADAOSMN1; SMN2 | |
| SCHEMBL8475762 | 0.70 | OXER1 (0.38) | PGRLMNASMN1; SMN2 | |
| SCHEMBL3202684 | 0.69 | MPO (0.44) | CYP1A2MEN1KMT2AHTR1ADRD2 | |
| SCHEMBL2084761 | 0.69 | ADORA3 (0.42) | CYP1A2MEN1KMT2APGRDAO | |
| SCHEMBL3210120 | 0.66 | KDM4E (0.49) | MEN1KMT2ALMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908844-A | N-substituted azabicycloalkane derivatives, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-01 | — | — | US | disclosed |