Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.53 |
| ▸ | ITGAV | P06756 | 9/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.51 |
| ▸ | ALPG | P10696 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464957 | 0.90 | SMN1; SMN2 (0.48) | ITGB3ITGAVTDP1ALPLALPG | |
| SCHEMBL8328333 | 0.78 | ALPL (0.64) | ALPLALPGPLAANPC1RAB9A | |
| SCHEMBL14025799 | 0.75 | ITGB3 (0.53) | ITGB3ITGAVTDP1ITGA2BPDK1 | |
| SCHEMBL5103778 | 0.73 | ATM (0.52) | ITGB3ITGAVTDP1ITGA2BPDK1 | |
| SCHEMBL11353994 | 0.73 | TDP1 (0.68) | TDP1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8471785 | 0.72 | ITGB3 (0.48) | ITGB3ITGAVTDP1ITGA2BPDK1 | |
| SCHEMBL14276925 | 0.71 | TDP1 (0.64) | TDP1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8468920 | 0.71 | TDP1 (0.50) | ITGB3ITGAVTDP1ITGA2BPDK1 | |
| SCHEMBL8325212 | 0.70 | TDP1 (0.49) | ITGB3ITGAVTDP1ITGA2BPDK1 | |
| SCHEMBL7091035 | 0.69 | ITGB3 (1.00) | ITGB3ITGAVTDP1ITGA2BPDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | claimed |
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |