Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067867 | 0.84 | POLB (0.49) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8471904 | 0.83 | POLB (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8472289 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL8066264 | 0.78 | MAPK1 (0.47) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL8061332 | 0.78 | HTT (0.53) | ALDH1A1SMN1; SMN2RAB9APOLBHPGD | |
| SCHEMBL8066284 | 0.76 | ALDH1A1 (0.45) | ALDH1A1RAB9AHPGDHTTTSHR | |
| SCHEMBL8472912 | 0.76 | HPGD (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8472144 | 0.73 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2RAB9AHTTCYP2C9 | |
| SCHEMBL8474666 | 0.73 | HPGD (0.63) | ALDH1A1SMN1; SMN2HPGDHTTCYP2C9 | |
| SCHEMBL8475470 | 0.73 | HPGD (0.59) | ALDH1A1SMN1; SMN2HPGDHTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994396-A | Furansulfonic acid derivatives and pharmaceutical compositions containing the same | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-30 | — | — | US | disclosed |