Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471948 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAKMT2AMEN1RCE1 | |
| SCHEMBL8472240 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKMT2AMEN1RCE1 | |
| SCHEMBL8472673 | 0.86 | HRH3 (0.48) | SMN1; SMN2LMNAKMT2AMEN1POLB | |
| SCHEMBL8475772 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKMT2ARCE1POLB | |
| SCHEMBL8472659 | 0.83 | MEN1 (0.59) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL8472467 | 0.82 | LTA4H (0.51) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL8472281 | 0.80 | HRH3 (0.47) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL8476781 | 0.77 | EPHX2 (0.48) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL8472571 | 0.77 | DRD2 (0.52) | KMT2AMEN1POLBAPOBEC3ACASP6 | |
| SCHEMBL8472345 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKMT2AMEN1RCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |