Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472659 | 0.90 | MEN1 (0.59) | LTA4HDRD2DRD3HRH3MEN1 | |
| SCHEMBL8472673 | 0.90 | HRH3 (0.48) | LTA4HDRD2DRD3HRH3MEN1 | |
| SCHEMBL8472281 | 0.87 | HRH3 (0.47) | LTA4HDRD2DRD3HRH3MEN1 | |
| SCHEMBL8472571 | 0.86 | DRD2 (0.52) | LTA4HDRD2DRD3HRH3MEN1 | |
| SCHEMBL8476781 | 0.85 | EPHX2 (0.48) | LTA4HDRD2DRD3HRH3MEN1 | |
| SCHEMBL8475163 | 0.84 | MEN1 (0.50) | LTA4HMEN1KMT2APOLBAPOBEC3A | |
| SCHEMBL8472465 | 0.82 | MEN1 (0.45) | MEN1KMT2APOLBAPOBEC3ACASP6 | |
| SCHEMBL8472242 | 0.82 | SMN1; SMN2 (0.46) | LTA4HHRH3MEN1KMT2APOLB | |
| SCHEMBL8473412 | 0.80 | LTA4H (0.51) | LTA4HHRH3MEN1KMT2APSMB1 | |
| SCHEMBL8473549 | 0.74 | POLB (0.45) | MEN1KMT2APOLBAPOBEC3ACASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |