Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.47 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.42 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473412 | 0.87 | LTA4H (0.51) | HRH3LTA4HESR1PSMB1HTT | |
| SCHEMBL8476147 | 0.87 | TSHR (0.49) | KDM4ELMNATP53SMN1; SMN2CNR1 | |
| SCHEMBL8477083 | 0.87 | CYP3A4 (0.49) | KDM4ETP53SMN1; SMN2CNR1CNR2 | |
| SCHEMBL8477094 | 0.86 | LTA4H (0.58) | HRH3LTA4HESR1PSMB1HTT | |
| SCHEMBL8477351 | 0.86 | HRH3 (0.48) | HRH3LTA4HESR1PSMB1HTT | |
| Hydrochloric Acid SCHEMBL8477102 | 0.85 | SMN1; SMN2 (0.40) | HTTKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL8472268 | 0.84 | MAPK1 (0.38) | KDM4EALDH1A1MAPK1SMN1; SMN2CNR1 | |
| SCHEMBL8472281 | 0.82 | HRH3 (0.47) | HRH3LTA4HBMPR1BBMPR1ATGFBR1 | |
| SCHEMBL8475983 | 0.82 | LTA4H (0.50) | HRH3LTA4HESR1HTTKDM4E | |
| SCHEMBL8474563 | 0.81 | LTA4H (0.50) | HRH3LTA4HESR1PSMB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |